Biosynthesis of hepatitis B virus e antigen: directed mutagenesis of the putative aspartyl protease site.

The C gene products of all mammalian hepadnaviruses contain a region with sequence similarities to the catalytic center of the aspartyl proteases. This region could have the capacity to cleave precore proteins, leading to the synthesis of e antigen. By site-directed mutagenesis on a plasmid containi...

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Detalles Bibliográficos

Publicado en:	J Virol
Principais autores:	Jean-Jean, O, Salhi, S, Carlier, D, Elie, C, De Recondo, A M, Rossignol, J M
Formato:	Artigo
Idioma:	Inglês
Publicado:	American Society for Microbiology (ASM) 1989
Assuntos:	Research Article
Acceso en liña:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC251224/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2685358/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.63.12.5497-5500.1989
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