Attenuation and cell culture adaptation of hepatitis A virus (HAV): a genetic analysis with HAV cDNA.

RNA transcripts of hepatitis A virus (HAV) HM-175 cDNA from attenuated, cell culture-adapted HAV were infectious in cell culture. A full-length HAV cDNA from wild-type HAV (propagated in marmosets in vivo) was constructed. Chimeric cDNAs that contained portions of both wild-type and attenuated genom...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Cohen, J I, Rosenblum, B, Feinstone, S M, Ticehurst, J, Purcell, R H
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1989
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC251203/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2555561/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.63.12.5364-5370.1989
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