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Interactive cloning with the SH3 domain of N-src identifies a new brain specific ion channel protein, with homology to Eag and cyclic nucleotide-gated channels

We have isolated a novel cDNA, that appears to represent a new class of ion channels, by using the yeast two-hybrid system and the SH3 domain of the neural form of Src (N-src) as a bait. The encoded polypeptide, BCNG-1, is distantly related to cyclic nucleotide-gated channels and the voltage-gated c...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Santoro, Bina, Grant, Seth G. N., Bartsch, Dusan, Kandel, Eric R.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 1997
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC25120/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9405696/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.26.14815
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