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Replication-dependent activation of the adenovirus major late promoter is mediated by the increased binding of a transcription factor to sequences in the first intron.

During lytic infection, the adenovirus major late promoter (MLP) is primarily activated after the onset of viral DNA replication. Using a combination of DNA binding and in vitro transcription assays, we delineated a discrete MLP element spanning positions +80 to +106 which is essential for the repli...

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Detalhes bibliográficos
Publicado no:J Virol
Principais autores: Jansen-Durr, P, Mondésert, G, Kédinger, C
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1989
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Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC251175/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2585599/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.63.12.5124-5132.1989
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