Virus mutation frequencies can be greatly underestimated by monoclonal antibody neutralization of virions.

Monoclonal antibody-resistant mutants have been widely used to estimate virus mutation frequencies. We demonstrate that standard virion neutralization inevitably underestimates monoclonal antibody-resistant mutant genome frequencies of vesicular stomatitis virus, due to phenotypic masking-mixing whe...

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Detaylı Bibliyografya
Asıl Yazarlar: Holland, J J, de la Torre, J C, Steinhauer, D A, Clarke, D, Duarte, E, Domingo, E
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 1989
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC251163/
https://ncbi.nlm.nih.gov/pubmed/2479770
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