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Duck hepatitis B virus can tolerate insertion, deletion, and partial frameshift mutation in the distal pre-S region.

In-frame and frameshift mutations were introduced into the pre-S region (1,212 base pairs) of duck hepatitis B virus. The in-frame mutants retained the inserted 12 nucleotides, while the frameshift mutants either reverted to wild type or exhibited a 10-nucleotide compensatory deletion downstream of...

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Bibliographic Details
Main Authors: Li, J S, Cova, L, Buckland, R, Lambert, V, Deléage, G, Trépo, C
Format: Artigo
Language:Inglês
Published: 1989
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC251147/
https://ncbi.nlm.nih.gov/pubmed/2552178
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