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Transfer of a mutant dihydrofolate reductase gene into pre- and postimplantation mouse embryos by a replication-competent retrovirus vector.

In order to explore the potential of retrovirus vectors for efficiently transferring foreign genes into mouse embryos, a replication-competent recombinant Moloney murine leukemia virus (Mo-MLV) vector carrying a mutant dihydrofolate reductase (DHFR) cDNA insert in the U3 region of the viral long ter...

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Bibliografische gegevens
Gepubliceerd in:J Virol
Hoofdauteurs: Stuhlmann, H, Jaenisch, R, Mulligan, R C
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology (ASM) 1989
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC251124/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2795720/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.63.11.4857-4865.1989
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