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Inhibition of rRNA synthesis by poliovirus: specific inactivation of transcription factors.

Synthesis of rRNA by RNA polymerase I is almost completely inhibited soon after infection of human cells with poliovirus. We show that extracts prepared from poliovirus-infected HeLa cells are severely inhibited in their ability to transcribe from a human rDNA promoter compared with extracts from mo...

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Bibliografiske detaljer
Main Authors: Rubinstein, S J, Dasgupta, A
Format: Artigo
Sprog:Inglês
Udgivet: 1989
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC251104/
https://ncbi.nlm.nih.gov/pubmed/2552146
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