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Processing the nonstructural polyproteins of sindbis virus: nonstructural proteinase is in the C-terminal half of nsP2 and functions both in cis and in trans.

The processing of the Sindbis virus nonstructural polyprotein translated in vitro has been studied. When Sindbis virus genomic RNA was translated in a reticulocyte lysate, polyprotein P123 was cleaved efficiently to produce nsP1, nsP2, and nsP3. Inhibition of this processing by anti-nsP2 antibodies,...

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Detalhes bibliográficos
Publicado no:J Virol
Principais autores: Hardy, W R, Strauss, J H
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1989
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC251099/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2529379/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.63.11.4653-4664.1989
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