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Tomoregulin Internalization Confers Selective Cytotoxicity of Immunotoxins on Prostate Cancer Cells

We have recently identified and validated the prostate cancer antigen Tomoregulin as a target for the radioimmunotherapy for prostate cancer. Here, we provide evidence that Tomoregulin is an internalizing antigen and a potential target for immunotoxins. First, the cell surface localization of Tomore...

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Main Authors: Zhao, Xiao-Yan, Liu, Hsiao-Lai, Liu, Bing, Willuda, Joerg, Siemeister, Gerhard, Mahmoudi, Mithra, Dinter, Harald
Formato: Artigo
Idioma:Inglês
Publicado: Neoplasia Press Inc. 2008
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2510815/
https://ncbi.nlm.nih.gov/pubmed/18633458
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