Interleukin-1 and tumor necrosis factor alpha can be induced from mononuclear phagocytes by human immunodeficiency virus type 1 binding to the CD4 receptor.

Cytokines such as interleukin-1 (IL-1) and tumor necrosis factor alpha (TNF alpha) are important in normal immune processes. In this study, we demonstrate that human immunodeficiency virus type 1 (HIV-1) virions induce normal peripheral blood mononuclear phagocytes to produce both IL-1 and TNF withi...

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Pubblicato in:	J Virol
Autori principali:	Merrill, J E, Koyanagi, Y, Chen, I S
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1989
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC251058/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2789293/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.63.10.4404-4408.1989
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