Both excision and replication of cloned autonomous parvovirus DNA require the NS1 (rep) protein.
When a bacterial plasmid containing the entire genome of LuIII virus except for the terminal 18 nucleotides from the right end is transfected into HeLa cells, the viral DNA is rescued and replicated, with production of infectious virus. This experimental system was used to examine the viral proteins...
Guardat en:
| Publicat a: | J Virol |
|---|---|
| Autor principal: | |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Microbiology (ASM)
1989
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC251039/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2528644/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.63.10.4249-4256.1989 |
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