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Leukemogenic membrane glycoprotein encoded by Friend spleen focus-forming virus: transport to cell surfaces and shedding are controlled by disulfide-bonded dimerization and by cleavage of a hydrophobic membrane anchor.

The leukemogenic glycoprotein (gp55) encoded by Friend spleen focus-forming virus is predominantly retained in the rough endoplasmic reticulum (RER). However, a small proportion (ca. 5%) is processed to form a derivative that occurs on plasma membranes and causes mitosis of infected erythroblasts. W...

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Библиографические подробности
Главные авторы: Gliniak, B C, Kabat, D
Формат: Artigo
Язык:Inglês
Опубликовано: 1989
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC250945/
https://ncbi.nlm.nih.gov/pubmed/2547985
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