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Chimeric picornavirus polyproteins demonstrate a common 3C proteinase substrate specificity.

Cross-species proteolytic processing was demonstrated by the 3C proteinases of human rhinovirus 14 and coxsackievirus B3 on poliovirus-specific polypeptide precursors. Chimeric picornavirus cDNA genomes were constructed in a T7 transcription vector in which the poliovirus 3C coding region was substi...

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Bibliographic Details
Main Authors: Dewalt, P G, Lawson, M A, Colonno, R J, Semler, B L
Format: Artigo
Language:Inglês
Published: 1989
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC250920/
https://ncbi.nlm.nih.gov/pubmed/2545915
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