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Herpes simplex virus alpha protein ICP27 possesses separable positive and negative regulatory activities.

The HSV-1 alpha (immediate-early) protein ICP27 expressed in transfected cells can activate the expression of certain HSV-1 promoters as well as inhibit the transactivated expression of others. We constructed a set of plasmids encoding mutant ICP27 molecules truncated at their carboxyl termini and u...

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Detalhes bibliográficos
Publicado no:J Virol
Principais autores: Rice, S A, Su, L S, Knipe, D M
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1989
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC250915/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2545913/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.63.8.3399-3407.1989
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