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Identification of cellular promoters by using a retrovirus promoter trap.

A retrovirus vector has been developed that selects for instances in which the provirus integrates in close proximity to cellular promoters. Coding sequences for a selectable marker (histidinol dehydrogenase) were inserted into the 3' long terminal repeat (LTR) of an enhancerless Molony murine...

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Autors principals: von Melchner, H, Ruley, H E
Format: Artigo
Idioma:Inglês
Publicat: 1989
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC250892/
https://ncbi.nlm.nih.gov/pubmed/2545900
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