Variation in simian immunodeficiency virus env is confined to V1 and V4 during progression to simian AIDS.

We have monitored changes in the simian immunodeficiency virus (SIV) envelope (env) gene in two macaques which developed AIDS after inoculation with a molecular clone of SIV. As the animals progressed to AIDS, selection occurred for viruses with variation in two discrete regions (V1 and V4) but not...

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Pubblicato in:	J Virol
Autori principali:	Overbaugh, J, Rudensey, L M, Papenhausen, M D, Benveniste, R E, Morton, W R
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1991
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC250821/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1942255/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.65.12.7025-7031.1991
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