Determination of the origin-specific DNA-binding domain of polyomavirus large T antigen.

To map the DNA-binding domain of polyomavirus large T antigen, we constructed a set of plasmids coding for unidirectional carboxy- or amino-terminal deletion mutations in the large T antigen. Analysis of origin-specific DNA binding by mutant proteins expressed in Cos-1 cells revealed that the C-term...

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Pubblicato in:	J Virol
Autori principali:	Sunstrom, N A, Acheson, N H, Hassell, J A
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1991
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC250815/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1658390/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.65.12.6998-7003.1991
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