A conserved coronavirus epitope, critical in virus neutralization, mimicked by internal-image monoclonal anti-idiotypic antibodies.

Monoclonal antibody (MAb) 6A.C3 neutralizes transmissible gastroenteritis coronavirus (TGEV) and is specific for a conserved epitope within subsite Ac of the spike (S) glycoprotein of TGEV. Six hybridomas secreting anti-idiotypic (Ab2) MAbs specific for MAb 6A.C3 (Ab1) have been selected. All six MA...

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Veröffentlicht in:	J Virol
Hauptverfasser:	Suñé, C, Smerdou, C, Antón, I M, Abril, P, Plana, J, Enjuanes, L
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 1991
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC250811/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1719237/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.65.12.6979-6984.1991
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