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Overlapping octamer and TAATGARAT motifs in the VF65-response elements in herpes simplex virus immediate-early promoters represent independent binding sites for cellular nuclear factor III.

Expression of the immediate-early (IE) genes of herpes simplex virus (HSV) is specifically stimulated by a 65-kilodalton virion transcription factor (VF65 or VP16) that is introduced as a component of infecting virions. In both the IE175(ICP4) and IE110(ICP0) promoters, this activation requires an u...

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Bibliografiske detaljer
Udgivet i:J Virol
Principais autores: apRhys, C M, Ciufo, D M, O'Neill, E A, Kelly, T J, Hayward, G S
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 1989
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC250783/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2542590/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.63.6.2798-2812.1989
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