The palindromic LTR-LTR junction of Moloney murine leukemia virus is not an efficient substrate for proviral integration.

We generated viral constructs to test the hypothesis that the major substrate on retroviral DNA that is utilized for proviral DNA integration is the palindromic sequence, termed the LTR-LTR junction, normally present in circular molecules formed by joining the two termini of linear proviral DNA. Rec...

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Vydáno v:J Virol
Hlavní autoři: Lobel, L I, Murphy, J E, Goff, S P
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 1989
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC250744/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2724412/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.63.6.2629-2637.1989
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