Direct measurement of the poliovirus RNA polymerase error frequency in vitro.

The fidelity of RNA replication by the poliovirus-RNA-dependent RNA polymerase was examined by copying homopolymeric RNA templates in vitro. The poliovirus RNA polymerase was extensively purified and used to copy poly(A), poly(C), or poly(I) templates with equimolar concentrations of noncomplementar...

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Veröffentlicht in:	J Virol
Hauptverfasser:	Ward, C D, Stokes, M A, Flanegan, J B
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 1988
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC250568/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2826815/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.62.2.558-562.1988
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