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Spatio-temporally controlled site-specific somatic mutagenesis in the mouse

The efficient introduction of somatic mutations in a given gene, at a given time, in a specific cell type will facilitate studies of gene function and the generation of animal models for human diseases. We have shown previously that conditional recombination–excision between two loxP sites can be ac...

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Detalhes bibliográficos
Main Authors: Brocard, Jacques, Warot, Xavier, Wendling, Olivia, Messaddeq, Nadia, Vonesch, Jean-Luc, Chambon, Pierre, Metzger, Daniel
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences of the USA 1997
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC25054/
https://ncbi.nlm.nih.gov/pubmed/9405652
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