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Quantitative basic residue requirements in the cleavage-activation site of the fusion glycoprotein as a determinant of virulence for Newcastle disease virus.

Newcastle disease virus exhibits a wide range of pathogenicity and virulence which, as with all paramyxoviruses, is directly related to the cleavability of a precursor (F0) of the fusion glycoprotein by cellular proteases. Sequence analyses of the cleavage site of several virulent and avirulent isol...

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Bibliografiske detaljer
Udgivet i:J Virol
Principais autores: Glickman, R L, Syddall, R J, Iorio, R M, Sheehan, J P, Bratt, M A
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 1988
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC250538/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3275436/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.62.1.354-356.1988
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