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Exploring the Limits of DNA Size: Naphtho-homologated DNA Bases and Pairs

A new design for DNA bases and base pairs is described in which the pyrimidine bases are widened by naphtho-homologation. Two naphtho-homologated deoxyribosides, dyyT (1) and dyyC (2) were synthesized and could be incorporated into oligonucleotides as suitably protected phosphoramidite derivatives....

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Lee, Alex H. F., Kool, Eric T.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2006
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2505348/
https://ncbi.nlm.nih.gov/pubmed/16834396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja0619004
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