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The Xenopus laevis Isoform of G Protein-Coupled Receptor 3 (GPR3) Is a Constitutively Active Cell Surface Receptor that Participates in Maintaining Meiotic Arrest in X. laevis Oocytes

Oocytes are held in meiotic arrest in prophase I until ovulation, when gonadotropins trigger a subpopulation of oocytes to resume meiosis in a process termed “maturation.” Meiotic arrest is maintained through a mechanism whereby constitutive cAMP production exceeds phosphodiesterase-mediated degrada...

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Hlavní autoři: Deng, James, Lang, Stephanie, Wylie, Christopher, Hammes, Stephen R.
Médium: Artigo
Jazyk:Inglês
Vydáno: The Endocrine Society 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2505325/
https://ncbi.nlm.nih.gov/pubmed/18511495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2008-0124
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