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In vitro mutagenesis identifies a region within the envelope gene of the human immunodeficiency virus that is critical for infectivity.

Site-specific mutagenesis was used to introduce amino acid substitutions at the asparagine codons of four conserved potential N-linked glycosylation sites within the gp120 envelope protein of human immunodeficiency virus (HIV). One of these alterations resulted in the production of noninfectious vir...

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Udgivet i:J Virol
Principais autores: Willey, R L, Smith, D H, Lasky, L A, Theodore, T S, Earl, P L, Moss, B, Capon, D J, Martin, M A
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 1988
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC250512/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3257102/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.62.1.139-147.1988
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