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The Epstein–Barr virus oncogene product latent membrane protein 1 engages the tumor necrosis factor receptor-associated death domain protein to mediate B lymphocyte growth transformation and activate NF-κB

The Epstein–Barr virus latent membrane protein 1 (LMP1) is essential for the transformation of B lymphocytes into lymphoblastoid cell lines. Previous data are consistent with a model that LMP1 is a constitutively activated receptor that transduces signals for transformation through its carboxyl-term...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Izumi, Kenneth M., Kieff, Elliott D.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1997
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC25049/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9356494/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.23.12592
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