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Benefit of Chondroitinase ABC on Sensory Axon Regeneration in a Laceration Model of Spinal Cord Injury in the Rat
BACKGROUND: Chondroitin sulfate proteoglycans (CSPGs) are upregulated in the spinal cord following spinal cord injury (SCI) creating a molecular barrier inhibitory to axon growth. Chondroitinase ABC (ChABC) degrades CSPGs in vitro and in vivo. METHODS: We studied whether intrathecal (IT) ChABC promo...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2504084/ https://ncbi.nlm.nih.gov/pubmed/18486695 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.surneu.2008.02.009 |
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