trans-acting viral protease is necessary and sufficient for activation of avian leukosis virus reverse transcriptase.

The structural and enzymatic components of retroviral cores are formed by proteolytic cleavage of precursor polypeptides, mediated by the viral protease (PR). We described previously the construction of PR-defective avian leukosis viruses. These mutant viruses are noninfectious, and their major inte...

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Bibliographic Details
Main Authors: Stewart, L, Vogt, V M
Format: Artigo
Language:Inglês
Published: 1991
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC250316/
https://ncbi.nlm.nih.gov/pubmed/1717719
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