Transgenic mouse lines that are immunologically tolerant and nontolerant to herpes simplex virus glycoprotein D.

A construct containing the gene for glycoprotein D of herpes simplex virus (HSV-gD), under the control of the simian virus 40 early promoter, was microinjected into single-cell embryos, and four transgenic mouse lines were established. Three were homozygous (lines 75, 111, and 113) and one was hemiz...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Abramczuk, J W, Kearns-Jonker, M, Monell-Torrens, E, Wohlenberg, C, Notkins, A L
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1991
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC250292/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1717714/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.65.11.6124-6128.1991
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