Immunization with baculovirus-expressed recombinant rotavirus proteins VP1, VP4, VP6, and VP7 induces CD8+ T lymphocytes that mediate clearance of chronic rotavirus infection in SCID mice.

Clearance of chronic murine rotavirus infection in SCID mice can be demonstrated by adoptive transfer of immune CD8+ T lymphocytes from histocompatible donor mice immunized with a murine homotypic rotavirus (T. Dharakul, L. Rott, and H.B. Greenberg, J. Virol 64:4375-4382, 1990). The present study fo...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Dharakul, T, Labbe, M, Cohen, J, Bellamy, A R, Street, J E, Mackow, E R, Fiore, L, Rott, L, Greenberg, H B
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1991
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC250256/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1656079/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.65.11.5928-5932.1991
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