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d-myo-Inositol 1,4,5,6-tetrakisphosphate produced in human intestinal epithelial cells in response to Salmonella invasion inhibits phosphoinositide 3-kinase signaling pathways

Several inositol-containing compounds play key roles in receptor-mediated cell signaling events. Here, we describe a function for a specific inositol polyphosphate, d-myo-inositol 1,4,5,6-tetrakisphosphate [Ins(1,4,5,6)P(4)], that is produced acutely in response to a receptor-independent process. Th...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Eckmann, Lars, Rudolf, Marco T., Ptasznik, Andrzej, Schultz, Carsten, Jiang, Tao, Wolfson, Nora, Tsien, Roger, Fierer, Joshua, Shears, Stephen B., Kagnoff, Martin F., Traynor-Kaplan, Alexis E.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1997
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC25019/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9405634/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.26.14456
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