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The prion model for [URE3] of yeast: Spontaneous generation and requirements for propagation

The genetic properties of the non-Mendelian element, [URE3], suggest that it is a prion (infectious protein) form of Ure2p, a mediator of nitrogen regulation in Saccharomyces cerevisiae. Into a ure2Δ strain (necessarily lacking [URE3]), we introduced a plasmid overproducing Ure2p. This induced the f...

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Detalhes bibliográficos
Main Authors: Masison, Daniel C., Maddelein, Marie-Lise, Wickner, Reed B.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1997
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC25018/
https://ncbi.nlm.nih.gov/pubmed/9356479
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