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Growth suppression of glioma cells by PTEN requires a functional phosphatase catalytic domain

Deletions of all or part of chromosome 10 are the most common genetic alterations in high-grade gliomas. The PTEN gene (also called MMAC1 and TEP1) maps to chromosome region 10q23 and has been implicated as a target of alteration in gliomas and also in other cancers such as those of the breast, pros...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Furnari, Frank B., Lin, Hong, Huang, H.-J. Su, Cavenee, Webster K.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1997
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC25009/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9356475/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.23.12479
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