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Alkenyl group is responsible for the disruption of microtubule network formation in human colon cancer cell line HT-29 cells

Alk(en)yl trisulfides (R-SSS-R′) are organosulfur compounds produced by crushed garlic and other Allium vegetables. We found that these compounds exhibit potent anticancer effects through the reaction with microtubules, causing cell cycle arrest. Nine alk(en)yl trisulfides including dimethyl trisulf...

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Detalhes bibliográficos
Main Authors: Hosono, Takashi, Hosono-Fukao, Tomomi, Inada, Kahoru, Tanaka, Rie, Yamada, Haruhisa, Iitsuka, Yuji, Seki, Taiichiro, Hasegawa, Isao, Ariga, Toyohiko
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2500214/
https://ncbi.nlm.nih.gov/pubmed/18515280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgn124
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