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Is antibiotic penetration compromised in the ischaemic tissues of patients undergoing amputation?

Antibiotic prophylaxis is indicated for patients undergoing amputation for severe ischaemia or gangrene. However, the adequacy of tissue levels of antibiotics in ischaemic tissue is not known. In this study the serum and tissue antibiotic levels were measured after intravenous administration of metr...

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Detalhes bibliográficos
Main Authors: Kerin, M. J., Greenstein, D., Chisholm, E. M., Sheehan, S. J., Kester, R. C.
Formato: Artigo
Idioma:Inglês
Publicado em: Royal College of Surgeons of England 1992
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2497617/
https://ncbi.nlm.nih.gov/pubmed/1416682
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