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Differentiation to the CCR2(+) Inflammatory Phenotype In Vivo Is a Constitutive, Time-Limited Property of Blood Monocytes and Is Independent of Local Inflammatory Mediators

It is proposed that CCR2(+) monocytes are specifically recruited to inflammatory sites, whereas CCR2(−) monocytes are recruited to normal tissue to become resident macrophages. Whether these subsets represent separate lineages, how differential trafficking is regulated and whether monocytes undergo...

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Detalhes bibliográficos
Main Authors: Xu, Heping, Manivannan, Ayyakkannu, Dawson, Rosemary, Crane, Isabel J., Mack, Matthias, Sharp, Peter, Liversidge, Janet
Formato: Artigo
Idioma:Inglês
Publicado em: 2005
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2496954/
https://ncbi.nlm.nih.gov/pubmed/16272351
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