T Cells' Immunological Synapses Induce Polarization of Brain Astrocytes In Vivo and In Vitro: A Novel Astrocyte Response Mechanism to Cellular Injury

BACKGROUND: Astrocytes usually respond to trauma, stroke, or neurodegeneration by undergoing cellular hypertrophy, yet, their response to a specific immune attack by T cells is poorly understood. Effector T cells establish specific contacts with target cells, known as immunological synapses, during...

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Detalhes bibliográficos
Main Authors: Barcia, Carlos, Sanderson, Nicholas S. R., Barrett, Robert J., Wawrowsky, Kolja, Kroeger, Kurt M., Puntel, Mariana, Liu, Chunyan, Castro, Maria G., Lowenstein, Pedro R.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2008
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2496894/
https://ncbi.nlm.nih.gov/pubmed/18714338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0002977
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