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High-resolution structure of the antibiotic resistance protein NimA from Deinococcus radiodurans
Many anaerobic human pathogenic bacteria are treated using 5-nitroimidazole-based (5-Ni) antibiotics, a class of inactive prodrugs that contain a nitro group. The nitro group must be activated in an anaerobic one-electron reduction and is therefore dependent on the redox system in the target cells....
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| Hlavní autoři: | , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
International Union of Crystallography
2008
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2496872/ https://ncbi.nlm.nih.gov/pubmed/18540048 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309108009901 |
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