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High-resolution structure of the antibiotic resistance protein NimA from Deinococcus radiodurans

Many anaerobic human pathogenic bacteria are treated using 5-nitroimidazole-based (5-Ni) antibiotics, a class of inactive prodrugs that contain a nitro group. The nitro group must be activated in an anaerobic one-electron reduction and is therefore dependent on the redox system in the target cells....

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Bibliografski detalji
Glavni autori: Leiros, Hanna-Kirsti S., Tedesco, Consiglia, McSweeney, Seán M.
Format: Artigo
Jezik:Inglês
Izdano: International Union of Crystallography 2008
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2496872/
https://ncbi.nlm.nih.gov/pubmed/18540048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309108009901
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