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trans-dominant inhibition of herpes simplex virus transcriptional regulatory protein ICP4 by heterodimer formation.

Herpes simplex virus encodes a 175-kilodalton immediate-early transactivating protein referred to as ICP4. A mutant ICP4 molecule expressed from a stable transformed cell line lacks the sequences required for transactivation yet retains the ability to specifically associate with DNA and to form homo...

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Détails bibliographiques
Publié dans:J Virol
Auteurs principaux: Shepard, A A, Tolentino, P, DeLuca, N A
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology (ASM) 1990
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC249687/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2164603/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.64.8.3916-3926.1990
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