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Crystallization and preliminary X-ray diffraction analysis of the carbohydrate-recognizing domain (VP8*) of bovine rotavirus strain NCDV

The infectivity of rotavirus is dramatically enhanced by proteolytic cleavage of its outer layer VP4 spike protein into two functional domains, VP8* and VP5*. The carbohydrate-recognizing domain VP8* is proposed to bind sialic acid-containing host cell-surface glycans and this is followed by a serie...

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Detalhes bibliográficos
Main Authors: Yu, Xing, Guillon, Annabel, Szyczew, Alex J., Kiefel, Milton J., Coulson, Barbara S., von Itzstein, Mark, Blanchard, Helen
Formato: Artigo
Idioma:Inglês
Publicado em: International Union of Crystallography 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2496849/
https://ncbi.nlm.nih.gov/pubmed/18540062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309108011949
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