Structural and immunological characterization of a linear virus-neutralizing epitope of the rabies virus glycoprotein and its possible use in a synthetic vaccine.

We have mapped a linear epitope recognized by the virus-neutralizing monoclonal antibody 6-15C4 within the primary sequence of the G protein from the Evelyn-Rokitnicki-Abelseth strain of rabies virus. This was accomplished by using fragments of the rabies virus G protein and deduced amino acid seque...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Dietzschold, B, Gore, M, Marchadier, D, Niu, H S, Bunschoten, H M, Otvos, L, Wunner, W H, Ertl, H C, Osterhaus, A D, Koprowski, H
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1990
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC249675/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1695255/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.64.8.3804-3809.1990
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