Substitution of the U3 long terminal repeat region of the neurotropic Cas-Br-E retrovirus affects its disease-inducing potential.

The Cas-Br-E and ts-Mo BA-1 murine leukemia viruses (MuLV) induce a spongiform neurodegenerative disease with different clinical manifestations, namely, either hind limb paralysis (Cas-Br-E) or tremors, spasticity, and hind limb weakness (ts-Mo Ba-1). We constructed the chimeric NEBA-1 MuLV by repla...

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Vydáno v:J Virol
Hlavní autoři: Paquette, Y, Kay, D G, Rassart, E, Robitaille, Y, Jolicoeur, P
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 1990
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC249669/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2164594/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.64.8.3742-3752.1990
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