Organ tropism of Sendai virus in mice: proteolytic activation of the fusion glycoprotein in mouse organs and budding site at the bronchial epithelium.

Wild-type Sendai virus is exclusively pneumotropic in mice, while a host range mutant, F1-R, is pantropic. The latter was attributed to structural changes in the fusion (F) glycoprotein, which was cleaved by ubiquitous proteases present in many organs (M. Tashiro, E. Pritzer, M. A. Khoshnan, M. Yama...

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Bibliografiske detaljer

Udgivet i:	J Virol
Principais autores:	Tashiro, M, Yamakawa, M, Tobita, K, Klenk, H D, Rott, R, Seto, J T
Format:	Artigo
Sprog:	Inglês
Udgivet:	American Society for Microbiology (ASM) 1990
Fag:	Research Article
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC249655/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2164589/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.64.8.3627-3634.1990
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