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Hormone-regulatable neoplastic transformation induced by a Jun-estrogen receptor chimera

The v-jun oncogene encodes a nuclear DNA binding protein that functions as a transcription factor and is part of the activator protein 1 complex. Oncogenic transformation by v-jun is thought to be mediated by the aberrant expression of specific target genes. To identify such Jun-regulated genes and...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Kruse, Ulrich, Iacovoni, Jason S., Goller, Martin E., Vogt, Peter K.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 1997
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC24963/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9356460/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.23.12396
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