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A method that allows the assembly of kinetochore components onto chromosomes condensed in clarified Xenopus egg extracts

Kinetochores are complex macromolecular structures that link mitotic chromosomes to spindle microtubules. Although a small number of kinetochore components have been identified, including the kinesins CENP-E and XKCM1 as well as cytoplasmic dynein, neither how these and other proteins are organized...

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Publicat a:Proc Natl Acad Sci U S A
Autors principals: Desai, Arshad, Deacon, Heather W., Walczak, Claire E., Mitchison, Timothy J.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 1997
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC24953/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9356457/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.23.12378
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