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Evidence suggesting that virulence maps to the P1 region of the coxsackievirus B4 genome.
A chimeric virus containing the P1 region of a virulent variant of coxsackievirus B4 and the P2 and P3 regions of a nonvirulent strain was constructed from cDNA clones. The chimeric virus induced pancreatitis with concurrent hypoglycemia similar to that observed in mice infected with the virulent va...
Gespeichert in:
| Veröffentlicht in: | J Virol |
|---|---|
| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Microbiology (ASM)
1990
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC249496/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2159563/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.64.6.3078-3081.1990 |
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