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In vivo EPR measurement of glutathione in tumor-bearing mice using improved disulfide biradical probe

Disulfide nitroxide biradicals, DNB, have been used for glutathione, GSH, measurements by X-band electron paramagnetic resonance, EPR, in various cells and tissues. In the present paper, the postulated potential use of DNB for EPR detection of GSH in vivo was explored. Isotopic substitution in the s...

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Main Authors: Roshchupkina, Galina I., Bobko, Andrey A., Bratasz, Anna, Reznikov, Vladimir A., Kuppusamy, Periannan, Khramtsov, Valery V.
Formato: Artigo
Idioma:Inglês
Publicado: 2008
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2494956/
https://ncbi.nlm.nih.gov/pubmed/18468522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2008.04.019
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