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Extreme Clonality in Lymphoblastoid Cell Lines with Implications for Allele Specific Expression Analyses

Lymphoblastoid cell lines (LCL) are being actively and extensively used to examine the expression of specific genes and genome-wide expression profiles, including allele specific expression assays. However, it has recently been shown that approximately 10% of human genes exhibit random patterns of m...

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Detalhes bibliográficos
Main Authors: Plagnol, Vincent, Uz, Elif, Wallace, Chris, Stevens, Helen, Clayton, David, Ozcelik, Tayfun, Todd, John A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2494943/
https://ncbi.nlm.nih.gov/pubmed/18698422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0002966
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